The Cowboys improved to 21-9 and 7-2 in the Big 12, while Kansas State fell to 10-19 and 0-9 in conference action.
"It is a great way to finish a weekend," said head coach Tom Holliday. "I am glad we got the win. Now we are into Tuesday and trying to build on our record."
OSU scored six runs in the first, three coming via a homer to right by second baseman Kenny Hansley, his first round-tripper of the year. John Urick plated the first two runs with a two-run single while catcher Jason Jaramillo's sacrifice fly scored the third tally.
The Wildcats scored a run in the second, but the Pokes answered right back with a run of their own, courtesy of a RBI single by centerfielder Jose Virgil. The Phoenix, Ariz., native would end the day going 4-for-5 at the plate with three runs scored. He also extended his hitting streak to 11 games.
KSU added another run in the fourth on a RBI single by Midwest City product and former Cowboy Gabe Luttrell. OSU countered with two runs of their own in the frame with a RBI single by Josh Fields and a steal of home by Virgil.
Kansas State would not give up and scored two runs in the top of the fifth, knocking out OSU starting pitcher Joe Weaver in the process. Weaver ended up giving up four runs in 4.2 innings of work with four strikeouts and five walks.
Oklahoma State added two runs in the bottom of the sixth to extend its lead to 11-4.
KSU took advantage of an error by shortstop Chris Gutierrez in the seventh to plate five runs and cut the lead to 11-9. Shortstop Brett Williams and centerfielder Terry Blunt both had RBI singles in the stanza, but designated hitter Brad Anzman provided the big blow with a three-run triple off of reliever Shane Hawk.
Hawk (6-0) gave up five unearned runs in the seventh but settled down in the eighth and struck out the first batter in the ninth, before giving way to Cowboy closer Daniel Rew. He walked Luttrell and pinch hitter Brian Patty reached on an error before Rew balked the runners to second and third. The Fayetteville, Ark., native struck out Blunt to end the game and picked up his fifth save of the season.
Rightfielder Lyndsey Simmons went 2-for-2 with three runs scored from the leadoff spot for OSU, while John Urick and leftfielder Scott Kirby both had two hits in the winning effort.
The Cowboys will continue its 11-game homestand with a pair of mid-week games against Arkansas State. The first game is on Tuesday, April 8 at 6 p.m., while game two is slated for a 2 p.m. start on Wednesday, April 9. OSU will be back in Big 12 play next weekend as Baylor comes to town for a three-game set.